Immunoglobin variable-region mRNA direct sequencing: a method to bypass aberrant myeloma light-chain transcripts.
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چکیده
منابع مشابه
Methylation and mRNA expression levels of P15, death-associated protein kinase, and suppressor of cytokine signaling-1 genes in multiple myeloma
Objective(s): The aim of this study was to investigate the methylation status and mRNA expression levels of P15, death-associated protein kinase (DAPK), and suppressor of cytokine signaling-1 (SOCS1) genes in multiple myeloma (MM). Materials and Methods: The bone marrow samples of 54 MM patients were collected and the methylation status of the P15, DAPK, and SOCS1 gene promoter regions was dete...
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Comparison of this sequence to the sequences of other, nondeleted human (Y chains and mouse y2a chains reveals that there are no deletions in the variable region (residues 1 to 115), the first domain of the constant region, Cal (residues 116 to 217), the hinge region (residues 218 to 240), or the CH~ domain (residues 241 to 330). However, the entire CH~ domain has been deleted. The failure of i...
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ورودعنوان ژورنال:
- BioTechniques
دوره 21 4 شماره
صفحات -
تاریخ انتشار 1996